SCHEMBL114121

SCHEMBL114121

COc1ccc(Br)c(N)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MAPT P10636 2/20 0.57
THRB P10828 2/20 0.57
TDP1 Q9NUW8 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
CYP3A4 P08684 3/20 0.52
NPC1 O15118 1/20 0.49
CASP3 P42574 1/20 0.49
RAB9A P51151 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3279318 0.98 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AMAPTTHRB
Bicarbonate SCHEMBL17416729 0.90 KMT2A (0.52) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL23202512 0.85 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL109386 0.84 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL1134723 0.80 CA1 (0.53) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL30250475 0.80 CA1 (0.53) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL29387850 0.78 ALDH1A1 (0.64) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL234263 0.78 ALDH1A1 (0.64) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL250035 0.78 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AMAPTTHRB
SCHEMBL22116837 0.77 MEN1 (0.55) ALDH1A1MEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993022-A Preparation method of bromoaniline UNIV SHANGHAI ENG SCIENCE 2013-03-27 CN claimed
US-8288552-B2 Dihydropyridone amidesas P2X7 modulators ROCHE PALO ALTO LLC (US) 2012-10-16 US claimed
CN-122071495-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
US-20260143903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-21 US disclosed
EP-4712958-A2 USE OF UROLITHIN DERIVATIVES IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS Vandria SA (CH) 2026-03-25 EP disclosed
EP-4688741-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES Meta-Immune, Inc. (KR) 2026-02-11 EP disclosed
US-12473269-B2 Urolithin derivatives and methods of use thereof VANDRIA SA (CH) 2025-11-18 US disclosed
WO-2025235874-A1 HETEROCYCLICS AS EGFR INHIBITORS SCHRÖDINGER, INC. (US) 2025-11-13 WO disclosed
US-12426496-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-23 US disclosed
US-20250282736-A1 SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR ST JUDE CHILDRENS RES HOSPITAL (US) 2025-09-11 US disclosed
US-12358884-B2 Urolithin derivatives and methods of use thereof VANDRIA SA (CH) 2025-07-15 US disclosed
WO-2001094341-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF TUMOURS ASTRAZENECA AB (SE) 2001-12-13 WO disclosed
EP-1003737-A1 PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2000-05-31 EP disclosed
WO-1999009024-A1 PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1999-02-25 WO disclosed
US-5576324-A Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same KOWA CO., LTD. (JP) 1996-11-19 US disclosed
EP-0638571-A1 QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME KOWA CO. LTD. (JP) 1995-02-15 EP disclosed
US-4895867-A 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents NORWICH EATON PHARMACEUTICALS, INC. (US) 1990-01-23 US disclosed
US-4882354-A N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents NORWICH EATON PHARMACEUTICALS, INC. (US) 1989-11-21 US disclosed
EP-0321431-A1 N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents Norwich Eaton Pharmaceuticals, Inc. (US) 1989-06-21 EP disclosed
EP-0251380-A2 2- (5-phenyl-2-furanyl) imidazoles useful as cardiotonic agents Norwich Eaton Pharmaceuticals, Inc. (US) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358884-B2 Urolithin derivatives and methods of use thereof NLN, UQCRC2, TUFM ALDH1A1 851/4885MEN1 3686/4885KMT2A 4346/4885
US-12426496-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device SLCO2A1, SLCO4C1, PIEZO1 ALDH1A1 153/4885MEN1 1283/4885KMT2A 2132/4885
US-20260143903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, GLRA3 ALDH1A1 2906/4885MEN1 4270/4885KMT2A 4150/4885
US-12473269-B2 Urolithin derivatives and methods of use thereof NLN, UQCRC2, TUFM ALDH1A1 851/4885MEN1 3686/4885KMT2A 4346/4885
US-20250282736-A1 SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR NR1H4, NR1I2, NR1I3 ALDH1A1 3469/4885MEN1 4207/4885KMT2A 4297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.