SCHEMBL11412876

SCHEMBL11412876

CCCc1ccccc1.N=C=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
ALDH1A1 P00352 2/20 0.43
CNR2 P34972 1/20 0.42
SIGMAR1 Q99720 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
ATM Q13315 1/20 0.41
KEAP1 Q14145 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1934354 1.00 TP53 (0.44) TP53ALDH1A1CNR2SIGMAR1HPGD
Carbimide SCHEMBL28286032 0.91 TP53 (0.48) TP53ALDH1A1SIGMAR1HPGDALOX15
Butylbenzyl SCHEMBL27793037 0.87 ALDH1A1 (0.50) ALDH1A1CNR2SIGMAR1HPGDHSD17B10
Butylbenzyl SCHEMBL11855936 0.87 ALDH1A1 (0.50) ALDH1A1CNR2SIGMAR1HPGDHSD17B10
Isothiocyanate SCHEMBL28944053 0.86 MIF (0.47) TP53ALDH1A1SIGMAR1HPGDALOX15
SCHEMBL43326 0.85 MAOA (0.50) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7604988 0.85 MAOA (0.50) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL28611995 0.85 KCNH2 (0.56) TP53ALDH1A1SIGMAR1HPGDHSD17B10
Benzene SCHEMBL3223041 0.85 TP53 (0.58) TP53ALDH1A1SIGMAR1HPGDALOX15
SCHEMBL40575 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110337328-A Catalyst composition and its use in aromatic alkylation process 埃克森美孚化学专利公司 2019-10-15 CN claimed
CN-110121485-A C3 fractionating system 沙特基础工业全球技术有限公司 2019-08-13 CN claimed
CN-106632940-A Polycarbodiimide compounds, preparation method thereof and liquid type hydrolysis-resistant agent composition 上海华峰新材料研发科技有限公司 2017-05-10 CN claimed
CN-114716772-A Microcellular foamed EPDM and preparation method thereof 台州学院 2022-07-08 CN disclosed
CN-110337328-A Catalyst composition and its use in aromatic alkylation process 埃克森美孚化学专利公司 2019-10-15 CN disclosed
CN-110214131-A Transalkylation process and catalyst composition therefor 埃克森美孚化学专利公司 2019-09-06 CN disclosed
CN-110214131-A Transalkylation process and catalyst composition therefor 埃克森美孚化学专利公司 2019-09-06 CN disclosed
CN-110139846-A Conversion of waste plastics to propylene and cumene 沙特基础全球技术有限公司 2019-08-16 CN disclosed
CN-110139845-A Conversion of the waste plastics to propylene and cumene 沙特基础全球技术有限公司 2019-08-16 CN disclosed
CN-110121485-A C3 fractionating system 沙特基础工业全球技术有限公司 2019-08-13 CN disclosed
CN-109475859-A Process for the preparation of monoalkylated aromatic compounds 埃克森美孚化学专利公司 2019-03-15 CN disclosed
CN-105849044-B The synthesis of ZSM-48 crystal 埃克森美孚研究工程公司 2018-10-26 CN disclosed
CN-108137433-A Prepare Alkylaromatics 巴杰许可有限责任公司 2018-06-08 CN disclosed
CN-106632940-A Polycarbodiimide compounds, preparation method thereof and liquid type hydrolysis-resistant agent composition 上海华峰新材料研发科技有限公司 2017-05-10 CN disclosed
CN-1556705-B 7,8,9,10-tetrahydro-6H-azepino, 6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2H-pyrrolo[2,1-b]-quinazolinone derivatives ACTELION PHARMACEUTICALS LTD 2010-04-28 CN disclosed
CN-1556705-A 7,8,9,10-tetrahydro-6H-azepino, 6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2H-pyrrolo[2,1-b]-quinazolinone derivatives ������˹ҩƷ��˾ 2004-12-22 CN disclosed
US-4238404-A N-CHLOROAMIDE, TERTIARY AMINE AKZONA INCORPORATED (US) 1980-12-09 US disclosed
US-4223145-A THERMAL DECOMPOSITION OF HYDROCHLORIDE OF TRISUBSTITUTED UREA AKZO N.V. (NL) 1980-09-16 US disclosed
US-3933701-A High resilience polyurethane foam OLIN CORPORATION (US) 1976-01-20 US disclosed