Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653675 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL11404540 | 0.78 | KMT2A (0.50) | POLBALDH1A1HDAC1HDAC6MAPT | |
| SCHEMBL12064898 | 0.78 | TDP1 (0.50) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL11408434 | 0.78 | RAPGEF4 (0.55) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11820221 | 0.78 | NPC1 (0.44) | ALDH1A1MAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL22966294 | 0.78 | MEN1 (0.36) | POLBALDH1A1HDAC1HDAC7HDAC8 | |
| SCHEMBL1155655 | 0.78 | ALDH1A1 (0.53) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9226189 | 0.78 | POLB (0.52) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL31549984 | 0.78 | ALDH1A1 (0.53) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30508518 | 0.78 | ALDH1A1 (0.53) | POLBALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4168279-A | Manufacture of amines of the formula Ar--NH--CH2 --R | BASF AKTIENGESELLSCHAFT (DE) | 1979-09-18 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-3982922-A | Herbicidal compositions containing furancarboxamides | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3944410-A | Substituted oxadiazolidine dione herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |