Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26431954 | 0.79 | TSHR (0.35) | MEN1GAAG6PDKMT2AL3MBTL1 | |
| SCHEMBL11414048 | 0.78 | POLB (0.54) | GAAKMT2APOLBALDH1A1HDAC1 | |
| SCHEMBL11820221 | 0.73 | NPC1 (0.44) | MEN1GAAKMT2AALDH1A1IDO1 | |
| SCHEMBL6653675 | 0.70 | ALDH1A1 (0.50) | MEN1GAAG6PDKMT2AALDH1A1 | |
| SCHEMBL11035424 | 0.69 | IDO1 (0.36) | MEN1GAAG6PDKMT2AL3MBTL1 | |
| SCHEMBL9691004 | 0.68 | CYP1A2 (0.47) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL11404540 | 0.68 | KMT2A (0.50) | MEN1KMT2APOLBALDH1A1HDAC1 | |
| SCHEMBL11408434 | 0.68 | RAPGEF4 (0.55) | MEN1GAAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12064898 | 0.68 | TDP1 (0.50) | MEN1KMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL21991721 | 0.68 | RAB9A (0.44) | MEN1GAAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | MEN1 901/4885GAA 4496/4885G6PD 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.