Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141441 | 1.00 | HRH3 (0.74) | HRH3KCNH2 | |
| SCHEMBL1128120 | 0.85 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL1128396 | 0.85 | KCNH2 (1.00) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL1141464 | 0.84 | KCNH2 (0.98) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL1141460 | 0.84 | KCNH2 (0.98) | HRH3KCNH2 | |
| SCHEMBL1939700 | 0.79 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL1938186 | 0.79 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL1939411 | 0.79 | KCNH2 (1.00) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL1939603 | 0.79 | KCNH2 (0.98) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL1939605 | 0.79 | KCNH2 (0.98) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110040105-A1 | PROCESSES USEFUL FOR THE SYNTHESIS OF (R)-1--2-METHYL-PYRROLIDINE | ARENA PHARMACEUTICALS, INC. (US) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040105-A1 | PROCESSES USEFUL FOR THE SYNTHESIS OF (R)-1--2-METHYL-PYRROLIDINE | DHPS, MRM1, ALDH18A1 | HRH3 2097/4885KCNH2 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.