Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415193 | 0.76 | MAPT (0.41) | CYP3A4SMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL11414720 | 0.73 | NR1H2 (0.44) | CYP3A4SMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL15363218 | 0.72 | USP2 (0.46) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| SCHEMBL15358131 | 0.70 | CYP3A4 (0.49) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| SCHEMBL5331916 | 0.68 | ALDH1A1 (0.52) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| SCHEMBL7304256 | 0.67 | CA12 (0.53) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| Ethyl Hematommate SCHEMBL12998324 | 0.67 | CYP3A4 (1.00) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| SCHEMBL27697949 | 0.67 | CA12 (0.53) | LMNAMAPTNPSR1ALDH1A1GAA | |
| Ethyl Hematommate SCHEMBL31350971 | 0.67 | CYP3A4 (1.00) | CYP3A4USP2SMN1; SMN2LMNAMAPT | |
| SCHEMBL522852 | 0.66 | ALDH1A1 (0.54) | CYP3A4USP2SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182877-A | ONE STEP CYCLIZATION OF UNSATURATED AMINO ACID, PHOSPHORUS OXYCHLORIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1980-01-08 | — | — | US | disclosed |