SCHEMBL7304256

SCHEMBL7304256

CCOC(=O)c1cc(Cl)c(C=O)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CYP3A4 P08684 2/20 0.49
USP2 O75604 1/20 0.49
ALOX15 P16050 1/20 0.48
ESR1 P03372 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
LMNA P02545 6/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 5/20 0.45
ALDH1A1 P00352 4/20 0.45
GAA P10253 1/20 0.45
NPSR1 Q6W5P4 2/20 0.45
PKM P14618 1/20 0.45
HTT P42858 1/20 0.45
ESR2 Q92731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15358131 0.92 CYP3A4 (0.49) CA12CA1CA2CA7CA9
SCHEMBL15358110 0.91 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL15358208 0.89 CA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL15358200 0.88 HSD17B2 (0.51) CA12CA1CA2CA7CA9
SCHEMBL15357923 0.87 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL16528153 0.85 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL16528598 0.83 ALDH1A1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL8950683 0.82 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL15320957 0.80 ALDH1A1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL691510 0.80 ESR1 (0.70) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-20080113305-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJIFILM CORPORATION 2008-05-15 US disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-5773456-A EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS SANOFI (FR) 1998-06-30 US disclosed
US-5578623-A DRUGS FOR TREATMENT OF ARTHRITIS, PANCREATITIS, CYSTIC FIBROSIS, BRONCHITIS, RESPIRATORY DISORDERS STERLING WINTHROP INC. (US) 1996-11-26 US disclosed
US-5380737-A Enzyme inhibitors STERLING WINTHROP INC. (US) 1995-01-10 US disclosed
EP-0542371-A1 Saccharin derivative proteolytic enzyme inhibitors STERLING WINTHROP INC. (US) 1993-05-19 EP disclosed