Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78145 | 0.85 | MAPT (0.61) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL11526941 | 0.85 | MAPT (0.61) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL3400048 | 0.85 | MAPT (0.61) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL11526739 | 0.82 | MAPT (0.63) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL12160707 | 0.82 | SMN1; SMN2 (0.59) | LMNAMAPTPOLBGAAALDH1A1 | |
| SCHEMBL12074647 | 0.80 | SMN1; SMN2 (0.57) | LMNAMAPTPOLBGAAALDH1A1 | |
| SCHEMBL18609347 | 0.79 | LMNA (0.45) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL24016961 | 0.79 | RAB9A (0.59) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL169760 | 0.79 | RAB9A (0.59) | LMNAMAPTPOLBGAATDP1 | |
| SCHEMBL7794044 | 0.79 | RAB9A (0.59) | LMNAMAPTPOLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210602-A | REDUCTIVE ALKYLATION OF PARA-NITROSO-DIPHENYLHYDROXYLAMINE | AKZONA INCORPORATED (US) | 1980-07-01 | — | — | US | disclosed |