Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455076 | 0.86 | KMT2A (0.56) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11415922 | 0.84 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11416394 | 0.76 | LMNA (0.48) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11415090 | 0.76 | MAPT (0.39) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11422283 | 0.74 | KMT2A (0.46) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL14535305 | 0.70 | MEN1 (0.50) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11775744 | 0.68 | KMT2A (0.61) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11070019 | 0.68 | TAS2R38 (0.48) | KMT2AMAPTMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4901515 | 0.68 | CYP1A2 (0.62) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL134948 | 0.68 | CYP1A2 (0.62) | KMT2AMAPTMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218396-A | ANTHELMINTICS, FUNGICIDES | E. R. SQUIBB & SONS, INC. (US) | 1980-08-19 | — | — | US | claimed |
| US-4218396-A | ANTHELMINTICS, FUNGICIDES | E. R. SQUIBB & SONS, INC. (US) | 1980-08-19 | — | — | US | disclosed |