Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455076 | 0.81 | KMT2A (0.56) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL10670402 | 0.79 | MEN1 (0.67) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL28025690 | 0.78 | MTOR (0.56) | ALDH1A1HSD17B10TP53TSHRMAPT | |
| SCHEMBL23618280 | 0.74 | ALDH1A1 (0.61) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL5448016 | 0.74 | ALDH1A1 (0.61) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL2230702 | 0.73 | ALDH1A1 (0.52) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL5455171 | 0.73 | MEN1 (0.71) | TAS2R38ALDH1A1HSD17B10MAPTCYP3A4 | |
| SCHEMBL31150164 | 0.70 | TAS2R38 (0.56) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL1814658 | 0.70 | TAS2R38 (0.58) | TAS2R38ALDH1A1HSD17B10TP53TYR | |
| SCHEMBL27574805 | 0.70 | CYP1A2 (0.56) | TAS2R38ALDH1A1HSD17B10TP53TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462821-A | 1-BENZOYL-3-THIOSEMICARBAZIDFES | GULF OIL CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0009324-B1 | SUBSTITUTED 1-BENZOYL-3-THIOSEMICARBAZIDES, THEIR MANUFACTURE AND USE AS PLANT GROWTH REGULANTS, AND AGRICULTURAL FORMULATIONS COMPRISING THEM | Gulf Oil Corporation (US) | 1982-07-21 | — | — | EP | disclosed |
| US-4282031-A | Substituted thiosemicarbazides, their manufacture and use as plant growth regulants | GULF OIL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0009324-A1 | Substituted 1-benzoyl-3-thiosemicarbazides, their manufacture and use as plant growth regulants, and agricultural formulations comprising them | Gulf Oil Corporation (US) | 1980-04-02 | — | — | EP | disclosed |