Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.49 |
| ▸ | CMA1 | P23946 | 12/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415880 | 1.00 | REN (0.49) | RENCMA1 | |
| Hydrochloric Acid SCHEMBL11422561 | 0.86 | LNPEP (0.40) | REN | |
| Hydrochloric Acid SCHEMBL11422563 | 0.86 | LNPEP (0.40) | REN | |
| SCHEMBL11426067 | 0.82 | PSENEN (0.46) | REN | |
| SCHEMBL11426063 | 0.82 | PSENEN (0.46) | REN | |
| SCHEMBL11038285 | 0.82 | XIAP (0.45) | REN | |
| SCHEMBL17287127 | 0.79 | REN (0.51) | RENCMA1 | |
| SCHEMBL19780925 | 0.79 | REN (0.56) | RENCMA1 | |
| SCHEMBL7264465 | 0.78 | F2 (0.44) | CMA1 | |
| SCHEMBL10826474 | 0.77 | CMA1 (0.58) | RENCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204991-A | Sarcosine1 dehydroalanine8 angiotensin II derivatives | G. D. SEARLE & CO. (US) | 1980-05-27 | — | — | US | disclosed |