Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 13/20 | 0.42 |
| ▸ | TRHR | P34981 | 2/20 | 0.41 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536244 | 0.87 | TRHR (0.49) | F2PRSS1ACETRHR | |
| SCHEMBL7273358 | 0.83 | ACE (0.49) | PRSS1ACECMA1TRHR | |
| SCHEMBL10826474 | 0.80 | CMA1 (0.58) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7355585 | 0.80 | F2 (0.54) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL29566322 | 0.80 | CMA1 (0.53) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL10826434 | 0.80 | CMA1 (0.58) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL28392404 | 0.80 | F2 (0.47) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL18103316 | 0.80 | F2 (0.47) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL11415874 | 0.78 | REN (0.49) | CMA1 | |
| SCHEMBL11415880 | 0.78 | REN (0.49) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |