Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.59 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.57 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.57 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.57 |
| ▸ | AHCY | P23526 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416011 | 1.00 | ADORA2B (0.69) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11409612 | 0.99 | ADORA2B (0.70) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11409631 | 0.99 | ADORA2B (0.70) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11518501 | 0.97 | ADORA2B (0.70) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL9494187 | 0.95 | ADORA2B (0.69) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11408861 | 0.85 | ADORA3 (0.67) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11416079 | 0.85 | ADORA2B (0.57) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11416067 | 0.85 | ADORA2B (0.57) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL11409857 | 0.85 | ADORA3 (0.70) | ADORA2BADORA3ADORA2AADORA1HSP90B1 | |
| SCHEMBL9493927 | 0.84 | ADORA3 (0.70) | ADORA2BADORA3ADORA2AADORA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224438-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-09-23 | — | — | US | disclosed |