Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Tryptophan SCHEMBL16390702 | 0.78 | KMT2A (0.80) | KMT2AMAPTKDM4EMEN1LMNA | |
| Dl-Tryptophan SCHEMBL1981755 | 0.78 | KMT2A (0.80) | KMT2AMAPTKDM4EMEN1LMNA | |
| Tryptophan SCHEMBL1981758 | 0.78 | KMT2A (0.80) | KMT2AMAPTKDM4EMEN1LMNA | |
| Tryptophan SCHEMBL1946948 | 0.77 | KMT2A (0.78) | KMT2AMAPTKDM4EMEN1LMNA | |
| Dl-Tryptophan SCHEMBL21179136 | 0.77 | KMT2A (0.78) | KMT2AMAPTKDM4EMEN1LMNA | |
| SCHEMBL1011575 | 0.77 | KDM4E (0.52) | KMT2AMAPTKDM4EMEN1LTA4H | |
| Tryptophan SCHEMBL23141133 | 0.74 | KMT2A (1.00) | KMT2AMAPTKDM4EMEN1LMNA | |
| Dl-Tryptophan SCHEMBL1120026 | 0.74 | KMT2A (1.00) | KMT2AMAPTKDM4EMEN1LMNA | |
| Tryptophan SCHEMBL289043 | 0.74 | KMT2A (1.00) | KMT2AMAPTKDM4EMEN1LMNA | |
| Dl-Tryptophan SCHEMBL7327 | 0.74 | KMT2A (1.00) | KMT2AMAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211840-A | USING ENZYME SPECIFIC FOR D-ISOMER OF 5-SUBSTITUTED HYDANTOIN | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-07-08 | — | — | US | disclosed |