Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079346 | 0.78 | CXCR4 (0.60) | CXCR4HDAC8CYP2A6GAATHRA | |
| D-Tryptophan SCHEMBL11417449 | 0.77 | KMT2A (0.54) | KDM4EMAPTLTA4HKDM1AALOX15 | |
| SCHEMBL6744208 | 0.73 | GSK3B (0.58) | KDM4EMAPTKDM1AMAOAMAOB | |
| SCHEMBL1011770 | 0.73 | THRA (0.48) | KDM4EMAPTCXCR4GAAALOX15 | |
| SCHEMBL4423961 | 0.73 | ADAMTS5 (0.45) | CXCR4GAANPSR1THRATHRB | |
| SCHEMBL29600642 | 0.73 | THRA (0.48) | KDM4EMAPTCXCR4GAAALOX15 | |
| SCHEMBL9828402 | 0.72 | TDP1 (0.50) | MAPTAHRNR4A2F7LTA4H | |
| SCHEMBL6704329 | 0.72 | PPARG (0.44) | KDM4ECXCR4HDAC8GAATHRA | |
| SCHEMBL14584233 | 0.71 | MAPT (0.81) | KDM4EMAPTKDM1AMAOAMAOB | |
| SCHEMBL1012031 | 0.70 | CXCR4 (0.53) | CXCR4HDAC8KDM1AGAATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | claimed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | claimed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | claimed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | claimed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | claimed |
| EP-1666588-B1 | NOVEL TRANSPORTER PROTEIN | AJINOMOTO KK (JP) | 2011-05-11 | — | — | EP | claimed |
| US-7320794-B2 | Transporter protein | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | claimed |
| US-20060183190-A1 | NOVEL TRANSPORTER PROTEIN | AJINOMOTO CO., INC. (JP) | 2006-08-17 | — | — | US | claimed |
| EP-1666588-A1 | NOVEL TRANSPORTER PROTEIN | Ajinomoto Co., Inc. (JP) | 2006-06-07 | — | — | EP | claimed |
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | claimed |
| EP-0159866-B1 | PROCESS FOR PRODUCTION OF L-AMINO ACIDS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0159866-A2 | Process for production of L-amino acids | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-30 | — | — | EP | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | claimed |
| JP-52015892-A | — | — | None | — | — | JP | disclosed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | disclosed |
| JP-S5215892-A | PROCESS FOR PREPARING L-TRYPTOPHAN | AJINOMOTO CO INC | 1977-02-05 | — | — | JP | disclosed |
| JP-S05215892-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183190-A1 | NOVEL TRANSPORTER PROTEIN | SLC12A5, SLC12A2, HM13 | KDM4E 1613/4885MAPT 2687/4885CXCR4 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.