Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418442 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNASRD5A2SMN1; SMN2HTT | |
| SCHEMBL28228751 | 0.82 | CES2 (0.41) | SMN1; SMN2ATMCES2CES1TCF4 | |
| SCHEMBL12657759 | 0.81 | ESR1 (0.51) | ALDH1A1SRD5A2TDP1ATMMEN1 | |
| SCHEMBL1825343 | 0.81 | ESR1 (0.51) | ALDH1A1SRD5A2TDP1ATMMEN1 | |
| SCHEMBL1825340 | 0.81 | ESR1 (0.51) | ALDH1A1SRD5A2TDP1ATMMEN1 | |
| SCHEMBL11426917 | 0.79 | SRD5A2 (0.52) | ALDH1A1LMNASRD5A2SMN1; SMN2HTT | |
| SCHEMBL11418451 | 0.79 | TCF4 (0.69) | ALDH1A1LMNASMN1; SMN2NPSR1HPGD | |
| SCHEMBL11427676 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTTDP1 | |
| SCHEMBL11422585 | 0.79 | TYR (0.44) | ALDH1A1LMNASMN1; SMN2HTTHPGD | |
| SCHEMBL11427678 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182730-A | Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes | GIVAUDAN CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |