Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418728 | 1.00 | LIG1 (0.58) | LIG1SLC5A1SLC5A2LMNAL3MBTL1 | |
| SCHEMBL11418715 | 0.83 | LIG1 (0.53) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL9723541 | 0.83 | LIG1 (0.53) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL11418668 | 0.78 | CA2 (0.52) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL11418665 | 0.78 | CA2 (0.52) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL11411247 | 0.77 | MEN1 (0.46) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL11411249 | 0.77 | MEN1 (0.46) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL5084597 | 0.75 | MAPT (0.50) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL5084594 | 0.75 | MAPT (0.50) | LIG1LMNAL3MBTL1CA1CA2 | |
| SCHEMBL5078670 | 0.73 | MAPT (0.49) | LIG1LMNAL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235929-A | TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT | WILLIAM H. RORER, INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4176198-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1979-11-27 | — | — | US | disclosed |