Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418715 | 1.00 | LIG1 (0.53) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL11418728 | 0.83 | LIG1 (0.58) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL11418732 | 0.83 | LIG1 (0.58) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL30373259 | 0.78 | CA2 (0.55) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL2322410 | 0.78 | CA2 (0.55) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL14337533 | 0.78 | CA2 (0.55) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL1238795 | 0.78 | CA2 (0.55) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL10628465 | 0.78 | POLB (0.51) | LIG1LMNAL3MBTL1CA2CA1 | |
| SCHEMBL11418898 | 0.78 | POLB (0.51) | LIG1LMNAL3MBTL1CA2CA1 | |
| Lithium Ion SCHEMBL3400785 | 0.77 | CA2 (0.53) | LIG1LMNAL3MBTL1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100532-A | In liquid hydrocarbonaceous media | BETZ LABORATORIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| US-4235929-A | TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT | WILLIAM H. RORER, INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4176198-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1979-11-27 | — | — | US | disclosed |