Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MPI | P34949 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628465 | 1.00 | POLB (0.51) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL1238795 | 0.86 | CA2 (0.55) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL30373259 | 0.86 | CA2 (0.55) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14337533 | 0.86 | CA2 (0.55) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL2322410 | 0.86 | CA2 (0.55) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11410350 | 0.85 | MAPT (0.46) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11410353 | 0.85 | MAPT (0.46) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| Lithium Ion SCHEMBL3400785 | 0.84 | CA2 (0.53) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14982912 | 0.79 | CA12 (0.57) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL13215048 | 0.79 | CA12 (0.81) | POLBALDH1A1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235929-A | TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT | WILLIAM H. RORER, INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4176198-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1979-11-27 | — | — | US | disclosed |