Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405956 | 0.84 | KMT2A (0.45) | CA1CA2CYP1A2ALDH1A1TSHR | |
| SCHEMBL4275848 | 0.81 | ALDH1A1 (0.59) | CA1CA2CYP1A2ALDH1A1TSHR | |
| SCHEMBL29404307 | 0.80 | PKM (0.42) | CA1CA2CYP1A2ALDH1A1GPR35 | |
| SCHEMBL11420061 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TP53SMN1; SMN2TDP1CYP3A4 | |
| SCHEMBL11879099 | 0.78 | ALDH1A1 (0.49) | CA1CA2ALDH1A1GPR35TP53 | |
| SCHEMBL28554520 | 0.78 | CASP6 (0.47) | CA1CA2CYP1A2ALDH1A1TSHR | |
| SCHEMBL29720550 | 0.74 | TDP1 (0.70) | CYP1A2ALDH1A1GPR35TP53TSHR | |
| SCHEMBL1649527 | 0.74 | CA1 (0.79) | CA1CA2CYP1A2ALDH1A1GPR35 | |
| SCHEMBL17375005 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TP53TDP1CYP3A4ALOX15 | |
| SCHEMBL28259289 | 0.73 | ERN1 (0.42) | CA1CA2ALDH1A1GPR35TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231799-A | MONOAZO DYES, MULTILAYER, CHARGE TRANSPORTING COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| US-4212813-A | OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4072520-A | ORGANIC DYES, XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | disclosed |
| US-3996049-A | XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3989520-A | XEROGRAPHY | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3977870-A | ORGANIC DYESTUFF LAYER | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |