Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423141 | 0.82 | CDK8 (0.50) | LTA4HTTBK1SCN9AMAPTCDK8 | |
| SCHEMBL751951 | 0.79 | MEN1 (0.44) | MAP4K4 | |
| SCHEMBL20176873 | 0.79 | TGFBR1 (0.46) | LTA4HSCN9ALMNAMAP4K4 | |
| SCHEMBL8737063 | 0.79 | TEAD4 (0.50) | MAPTNPSR1MAP4K4 | |
| SCHEMBL16539484 | 0.79 | GRM4 (0.55) | LTA4HTTBK1SCN9AKCNH2SCN5A | |
| SCHEMBL27428 | 0.78 | KMT2A (0.47) | MAPTNPSR1 | |
| SCHEMBL29497438 | 0.78 | KMT2A (0.47) | MAPTNPSR1 | |
| SCHEMBL11148692 | 0.78 | CA1 (0.52) | LTA4HSCN9AKCNH2SCN5AMAPT | |
| SCHEMBL1685383 | 0.78 | CA1 (0.52) | LTA4HSCN9AKCNH2SCN5AMAPT | |
| SCHEMBL509776 | 0.77 | LTA4H (0.50) | LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229448-A | 5-Substituted picolinic acid derivatives and an anti-hypertensive composition containing the same | MEUJI SEIKA KAISHA LTD. (JP) | 1980-10-21 | — | — | US | disclosed |