SCHEMBL1685383

SCHEMBL1685383

FC(F)(F)c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
LTA4H P09960 2/20 0.52
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
PDE4A P27815 1/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
KIF11 P52732 3/20 0.47
KCNH2 Q12809 2/20 0.46
SCN9A Q15858 2/20 0.46
MAPK14 Q16539 1/20 0.46
SCN5A Q14524 1/20 0.46
RAB9A P51151 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOB P27338 1/20 0.45
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148692 1.00 CA1 (0.52) CA1CA2CA9LTA4HALDH1A1
SCHEMBL29377645 0.97 LTA4H (0.50) CA1CA2CA9LTA4HALDH1A1
SCHEMBL254896 0.90 TSHR (0.59) LTA4HALDH1A1TSHRKIF11KCNH2
SCHEMBL7938383 0.90 LTA4H (0.46) CA1CA2CA9LTA4HPDE4A
SCHEMBL9064756 0.88 RAB9A (0.61) CA1CA2CA9LTA4HALDH1A1
SCHEMBL9827725 0.88 CA1 (0.48) CA1CA2CA9LTA4HALDH1A1
SCHEMBL9987935 0.88 TRPV1 (0.46) CA1CA2CA9LTA4HALDH1A1
SCHEMBL8684058 0.88 CA1 (0.48) CA1CA2CA9LTA4HALDH1A1
SCHEMBL2098374 0.88 LTA4H (0.45) CA1CA2CA9LTA4HALDH1A1
SCHEMBL1765673 0.88 KIF11 (0.64) LTA4HPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031639-A Preparation method of biphosphonate with P-O-C-P structure 烟台大学 2022-02-11 CN claimed
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN claimed
CN-104927072-A Solvent-resistant polyimide thin film with low thermal expansion coefficient and preparation method for polyimide thin film LU AN CITY DUERBANG INSULATION MATERIALS CO LTD 2015-09-23 CN claimed
CN-115703698-B Preparation method of trifluoro vinyl alkyl ether compound and intermediate thereof 中国科学院上海有机化学研究所 2025-01-24 CN disclosed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN disclosed
CN-115703698-A Preparation method of trifluorovinyl alkyl ether compound and intermediate thereof 中国科学院上海有机化学研究所 2023-02-17 CN disclosed
CN-111303150-B High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2021-10-19 CN disclosed
CN-109111572-B Polyimide polymer and polyimide film 台虹科技股份有限公司 2020-12-01 CN disclosed
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN disclosed
US-10167300-B2 Metalloenzyme inhibitor compounds as fungicides DOW AGROSCIENCES LLC (US) 2019-01-01 US disclosed
US-20180298038-A1 METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-10-18 US disclosed
US-20040249172-A1 Process for the preparationof prostaglandins and analogues thereof RESOLUTION CHEMICALS LIMITED (GB) 2004-12-09 US disclosed
EP-1389198-A2 PROCESS FOR THE PREPARATION OF PROSTAGLANDINS AND ANALOGUES THEREOF Resolution Chemicals Limited (GB) 2004-02-18 EP disclosed
WO-2002096898-A2 PROCESS FOR THE PREPARATION OF PROSTAGLANDINS AND ANALOGUES THEREOF RESOLUTION CHEMICALS LIMITED (GB) 2002-12-05 WO disclosed
US-6239289-B1 PERFLUOROALKYLATING A NUCLEOPHILE; STABILITY DAIKIN INDUSTRIES LTD. (JP) 2001-05-29 US disclosed
EP-1013651-A1 O-(PERFLUOROALKYL)DIBENZOFURANIUM SALT DERIVATIVES, INTERMEDIATES FOR THE PREPARATION OF THE SAME, PROCESS FOR THE PREPARATION OF THE INTERMEDIATES, PERFLUOROALKYLATING AGENTS, AND PROCESS FOR PERFLUOROALKYLATION Daikin Industries, Limited (JP) 2000-06-28 EP disclosed
EP-0188031-B1 NOVEL SUBSTITUTED PHENYL ETHERS, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THE PREPARATION OF SUBSTITUTED PHENOLS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-09-14 EP disclosed
US-4607128-A Novel substituted phenyl ethers, process for their preparation, and their use in the preparation of substituted phenols SHELL OIL COMPANY (US) 1986-08-19 US disclosed
EP-0188031-A1 Novel substituted phenyl ethers, process for their preparation, and their use in the preparation of substituted phenols SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-07-23 EP disclosed
US-4280834-A Novel diphenyl ether derivative and herbicidal composition containing the same as an active component NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167300-B2 Metalloenzyme inhibitor compounds as fungicides GPX1, POR, MGAM CA1 257/4885CA2 85/4885CA9 199/4885
US-20040249172-A1 Process for the preparationof prostaglandins and analogues thereof PTGIS, PTGES, PTGES2 CA1 4199/4885CA2 3833/4885CA9 3753/4885
US-20180298038-A1 METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES GPX1, POR, MGAM CA1 257/4885CA2 85/4885CA9 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.