Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13337725 | 0.92 | NOS3 (0.55) | NOS3NOS2NOS1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL11420925 | 0.90 | NOS3 (0.53) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL2552826 | 0.85 | NOS2 (0.52) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL31280277 | 0.83 | NOS3 (0.50) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL2550616 | 0.83 | NOS3 (0.50) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL22300397 | 0.82 | TDP1 (0.51) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL2555626 | 0.81 | KCNH2 (0.48) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL30019258 | 0.81 | KCNH2 (0.48) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL27630660 | 0.81 | KCNH2 (0.48) | NOS3NOS2NOS1KDM4ETSHR | |
| Tetradecane SCHEMBL27660314 | 0.81 | KCNH2 (0.48) | NOS3NOS2NOS1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222951-A | HALOGEN-HETEROCYCLE-PLATINUM COMPLEXES AS CATALYSTS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-09-16 | — | — | US | disclosed |