Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183009 | 0.98 | NQO2 (0.57) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL20475325 | 0.91 | RAB9A (0.53) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL31643056 | 0.91 | RAB9A (0.53) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| Sulfuric Acid SCHEMBL10827277 | 0.86 | ALDH1A1 (0.53) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| Sulfuric Acid SCHEMBL10827282 | 0.86 | ALDH1A1 (0.53) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL17483584 | 0.82 | NQO2 (0.68) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL17483582 | 0.82 | NQO2 (0.68) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL12578240 | 0.81 | RAB9A (0.49) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL31031113 | 0.80 | NQO2 (0.49) | NQO2MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL997540 | 0.80 | NQO2 (0.49) | NQO2MAPTRAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210390-A | Electrochromic composition and electrochromic display device using same | DAI NIPPON TORYO CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |