Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10827282 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL31031113 | 0.90 | NQO2 (0.49) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL3129032 | 0.90 | NQO2 (0.49) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL997540 | 0.90 | NQO2 (0.49) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL183009 | 0.88 | NQO2 (0.57) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| Bromide SCHEMBL11421481 | 0.86 | NQO2 (0.55) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| Sulfuric Acid SCHEMBL29106385 | 0.82 | MAPT (0.50) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL20475325 | 0.82 | RAB9A (0.53) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| SCHEMBL31643056 | 0.82 | RAB9A (0.53) | ALDH1A1MAPTRAB9AMAPK1CYP1A2 | |
| Phenazine SCHEMBL8564741 | 0.79 | MAPT (0.65) | ALDH1A1MAPTRAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610767-A | Photochemical method for preparing 4-keto-9-methylphenazine | LATVIISKY GOSUDARSTVENNY UNIVERSITET IMENI P.STUCHKI (SU) | 1986-09-09 | — | — | US | disclosed |