SCHEMBL1142153

SCHEMBL1142153

C=C(CCCC(C)OC(=O)CC(C)=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142576 0.90 MGAM (0.36) FAAHCNR1CNR2MGAMGAA
SCHEMBL5605894 0.86 MGAM (0.35) MGAMGAASIMGAM2
SCHEMBL944289 0.80 MGAM (0.39) FAAHCNR1CNR2MGAMGAA
SCHEMBL6252512 0.79 CHRNB2 (0.33) FAAHCNR1CNR2
SCHEMBL3819166 0.79 MGAM (0.38) MGAMGAASIMGAM2
SCHEMBL8751683 0.77 MGAM (0.50) FAAHCNR1CNR2MGAMGAA
SCHEMBL2728978 0.76 FAAH (0.58) FAAHCNR1CNR2MGAMGAA
SCHEMBL16473522 0.76 FAAH (0.46) FAAHCNR1CNR2MGAMGAA
SCHEMBL388923 0.76 TET2 (0.32)
SCHEMBL22615771 0.75 FAAH (0.61) FAAHCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110028645-A1 STAIN-PROOFING AGENTS, COATING COMPOSITIONS COMPRISING THE STAIN-PROOFING AGENTS AND COATED ARTICLES ASAHI GLASS COMPANY LIMITED (JP) 2011-02-03 US disclosed
EP-1256611-B1 Aqueous dispersion and coated product JSR CORP (JP) 2009-07-29 EP disclosed
US-7417090-B2 Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof DAINIPPON INK & CHEMICALS, INC. (JP) 2008-08-26 US disclosed
US-20070049691-A1 Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-03-01 US disclosed
US-20060100387-A1 Stain-proofing agents, coating compositions comprising the stain-proofing agents and coated articles ASAHI GLASS COMPANY LIMITED (JP) 2006-05-11 US disclosed
US-6953821-B2 Aqueous dispersion, process for production thereof and coated substances JSR CORPORATION (JP) 2005-10-11 US disclosed
US-6726997-B2 WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS JSR CORPORATION (JP) 2004-04-27 US disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
US-20030045626-A1 Aqueous dispersion, process for production thereof and coated substances JSR CORPORATION (JP) 2003-03-06 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
EP-1172412-A1 AQUEOUS DISPERSION, PROCESS FOR PRODUCTION THEREOF AND COATED SUBSTANCES JSR Corporation (JP) 2002-01-16 EP disclosed