SCHEMBL3819166

SCHEMBL3819166

C=C(CCC(OC(=O)CC(C)=O)OC(=O)CC(C)=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605894 0.90 MGAM (0.35) MGAMGAASIMGAM2
SCHEMBL1142576 0.85 MGAM (0.36) MGAMGAASIMGAM2
SCHEMBL9505136 0.82 MGAM (0.40) MGAMGAASIMGAM2
SCHEMBL1141992 0.82 MGAM (0.34) MGAMGAASIMGAM2
SCHEMBL195261 0.80 ALDH1A1 (0.36) MGAMGAASIMGAM2
SCHEMBL1142153 0.79 FAAH (0.40) MGAMGAASIMGAM2
SCHEMBL944289 0.74 MGAM (0.39) MGAMGAASIMGAM2
SCHEMBL2381597 0.74 MGAM (0.46) MGAMGAASIMGAM2
SCHEMBL481261 0.74 TET2 (0.35)
SCHEMBL183780 0.73 MGAM (0.41) MGAMGAASIMGAM2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581274-B1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSIST PUBL HOPITAUX DE PARIS (FR) 2009-08-05 EP claimed
EP-1581274-A1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSISTANCE PUBLIQUE, HOPITAUX DE PARIS (FR) 2005-10-05 EP claimed
WO-2004069294-A1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2004-08-19 WO claimed
EP-0927751-B1 Smear resistant pigmented ink jet inks containing Beta-diketone or ureido dispersants DU PONT (US) 2002-09-11 EP claimed
EP-0258988-B1 MASTIC AND CAULKING COMPOSITIONS AND COMPOSITE ARTICLES ROHM AND HAAS COMPANY (US) 1993-06-16 EP claimed
EP-1581274-B1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSIST PUBL HOPITAUX DE PARIS (FR) 2009-08-05 EP disclosed
US-20070100081-A1 Polymer compositions having novel cure systems and method of making articles with same DOW REICHHOLD SPECIALTY LATEX LLC 2007-05-03 US disclosed
EP-1581274-A1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSISTANCE PUBLIQUE, HOPITAUX DE PARIS (FR) 2005-10-05 EP disclosed
WO-2004069294-A1 INJECTABLE GEL-FORMING COMPOSITIONS BASED ON CROSS-LINKED AND NON-CROSS-LINKED POLYMERS AND THE USE THEREOF ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2004-08-19 WO disclosed
EP-0653469-A2 Aqueous coating compositions based on room-temperature crosslinking latex RHONE-POULENC SPECIALTY CHEMICALS CO. (US) 1995-05-17 EP disclosed