Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436023 | 0.83 | CA2 (0.49) | ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL9727278 | 0.77 | TSHR (0.54) | ALDH1A1TSHRPOLBFKBP1AALOX5 | |
| SCHEMBL22209505 | 0.77 | CCR1 (0.54) | — | |
| SCHEMBL18621674 | 0.77 | CCR1 (0.54) | — | |
| SCHEMBL3548419 | 0.76 | FKBP1A (0.47) | ALDH1A1HPGDFKBP1APDK2SMN1; SMN2 | |
| SCHEMBL3548417 | 0.76 | FKBP1A (0.47) | ALDH1A1HPGDFKBP1APDK2SMN1; SMN2 | |
| SCHEMBL3544644 | 0.75 | PDK2 (0.47) | ALDH1A1TSHRHPGDPOLBPDK2 | |
| SCHEMBL3544643 | 0.75 | PDK2 (0.47) | ALDH1A1TSHRHPGDPOLBPDK2 | |
| SCHEMBL26246255 | 0.75 | CNR2 (0.52) | ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL3547033 | 0.75 | POLB (0.48) | HPGDPOLBPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217130-A | DECREASING ACID CONTENT WITH PHENYL- OR BENZYLCARBAMOYLPROLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1980-08-12 | — | — | US | disclosed |