SCHEMBL9727278

SCHEMBL9727278

COC(=O)C1CCCN1C(=O)C(Cl)c1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
ALDH1A1 P00352 2/20 0.50
PEPD P12955 3/20 0.48
XPNPEP1 Q9NQW7 2/20 0.48
CCR1 P32246 1/20 0.46
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
MMP13 P45452 1/20 0.44
ADAM17 P78536 1/20 0.44
FKBP1A P62942 2/20 0.44
POLB P06746 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ALOX5 P09917 1/20 0.42
EP300 Q09472 1/20 0.41
CREBBP Q92793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9727329 0.83 ALDH1A1 (0.52) TSHRALDH1A1PEPDXPNPEP1FKBP1A
SCHEMBL9727475 0.83 ALDH1A1 (0.52) TSHRALDH1A1PEPDXPNPEP1FKBP1A
SCHEMBL9727523 0.81 ALDH1A1 (0.46) ALDH1A1PEPDXPNPEP1FKBP1APOLB
SCHEMBL11422425 0.77 ALDH1A1 (0.52) TSHRALDH1A1FKBP1APOLBALOX5
SCHEMBL22209505 0.77 CCR1 (0.54) CCR1
SCHEMBL18621674 0.77 CCR1 (0.54) CCR1
SCHEMBL26210944 0.76 ALDH1A1 (0.47) TSHRALDH1A1MMP1MMP3MMP13
SCHEMBL9727448 0.76 PEPD (0.49) ALDH1A1PEPDXPNPEP1FKBP1APOLB
SCHEMBL26210945 0.75 DPP4 (0.58) ALDH1A1PEPD
SCHEMBL18620690 0.75 CCR1 (0.45) TSHRALDH1A1PEPDXPNPEP1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142065-A Intermediates for herbicides, fungicides, miticides and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091537-A Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4985063-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed