Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423110 | 0.88 | KMT2A (0.50) | LPAR1LPAR5 | |
| SCHEMBL11420524 | 0.78 | P4HTM (0.54) | P4HTMLPAR1LPAR5 | |
| SCHEMBL5755276 | 0.77 | P4HTM (0.63) | P4HTM | |
| SCHEMBL30440468 | 0.77 | LIPE (0.50) | P4HTMASPH | |
| SCHEMBL16539505 | 0.77 | LTA4H (0.46) | — | |
| SCHEMBL11410233 | 0.77 | LIPE (0.50) | P4HTMASPH | |
| SCHEMBL11521654 | 0.75 | LTA4H (0.58) | RXRARXRBRXRGLPAR1LPAR5 | |
| SCHEMBL753336 | 0.74 | P4HTM (0.53) | P4HTM | |
| SCHEMBL11412080 | 0.74 | CDK8 (0.55) | MRGPRX4KMOPPARG | |
| SCHEMBL12071339 | 0.73 | LYN (0.48) | RXRARXRBRXRGLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229448-A | 5-Substituted picolinic acid derivatives and an anti-hypertensive composition containing the same | MEUJI SEIKA KAISHA LTD. (JP) | 1980-10-21 | — | — | US | disclosed |