Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416851 | 1.00 | DHODH (0.44) | DHODHPTPN11KDM4EALDH1A1TSHR | |
| SCHEMBL11402270 | 0.84 | ALDH1A1 (0.52) | DHODHKDM4EALDH1A1TSHRPTGS2 | |
| SCHEMBL11418971 | 0.81 | CA2 (0.54) | KDM4ETSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL11418973 | 0.81 | CA2 (0.54) | KDM4ETSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL11409847 | 0.78 | DHODH (0.64) | DHODHKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11221559 | 0.77 | PTGS2 (0.50) | KDM4EALDH1A1TSHRPTGS2MEN1 | |
| SCHEMBL11221569 | 0.77 | PTGS2 (0.50) | KDM4EALDH1A1TSHRPTGS2MEN1 | |
| SCHEMBL11423177 | 0.77 | ALDH1A1 (0.45) | DHODHKDM4EALDH1A1PTGS2MEN1 | |
| SCHEMBL11423175 | 0.77 | ALDH1A1 (0.45) | DHODHKDM4EALDH1A1PTGS2MEN1 | |
| SCHEMBL11409867 | 0.77 | DHODH (0.48) | DHODHPTPN11KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |