SCHEMBL1142371

SCHEMBL1142371

[CH2]CCCCOC(=O)C(=C)C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.68
THRB P10828 1/20 0.53
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 1/20 0.35
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
NAAA Q02083 1/20 0.33
LMNA P02545 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 1/20 0.32
EPHX1 P07099 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227734 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1228562 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL33382 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1142983 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL329015 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9357929 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL33312 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1228461 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10437170 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27459407 0.98 TSHR (0.71) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4308520-A1 CHEMICAL WALL PLUG ON ISOCYANATE-AMINE BASIS WITH IMPROVED STRENGTH, AND USE THEREOF Hilti Aktiengesellschaft (LI) 2024-01-24 EP claimed
CN-110120548-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-110117417-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-110120551-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-110120549-A Polymer dielectric film and preparation method thereof and lithium ion battery 比亚迪股份有限公司 2019-08-13 CN claimed
CN-107501476-B A kind of preparation method of photo-crosslinking antibiotic property composite membrane of polyvinyl alcohol 江南大学 2019-07-30 CN claimed
EP-2801401-B1 OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR LG CHEMICAL LTD (KR) 2018-12-12 EP claimed
CN-108461607-A Light-emitting device and image display device 夏普株式会社 2018-08-28 CN claimed
CN-107012450-A A kind of method of polymeric substrate surface metallization and application thereof 中国科学院深圳先进技术研究院 2017-08-04 CN claimed
CN-106735970-A A kind of welder and its welding method based on Plasma MIG control systems 江苏建筑职业技术学院 2017-05-31 CN claimed
CN-106462071-A Photosensitive resin composition for light shielding and light-shielding layer formed therefrom 三养社 2017-02-22 CN claimed
US-7517471-B2 And benzo[1,2-b:3,4-b']difuran derivatives; liquid crystal media, electrooptical displays; negative Delta epsilon, vertically alligned thin film transistors MERCK PATENT GMBH (DE) 2009-04-14 US claimed
US-7442419-B2 Comprising one or more dielectrically positive compounds having a dielectric anisotropy of more than 3; twisted Nematic (TN) or Plane Switching (IPS) type; low rotational viscosity; polycyclo cyclohexyl fluorocarbon benzyl ether derivatives, electrooptics MERCK PATENT GMBH (DE) 2008-10-28 US claimed
US-20070228327-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2007-10-04 US claimed
EP-0461651-B1 Recording medium FUJI PHOTO FILM CO LTD (JP) 1994-02-16 EP claimed
EP-0537972-A1 Treating solution for contact lenses NOF CORPORATION (JP) 1993-04-21 EP claimed
CN-1061033-A The gel acid that acidifying strata is used SICHUAN PETROLEUM ADMINISTRATION (CN) 1992-05-13 CN claimed
EP-4381345-A1 SWITCHING LAYERS FOR USE IN A WINDOW ELEMENT Merck Patent GmbH (DE) 2024-06-12 EP disclosed
WO-1988010251-A1 ARYL SULPHUR PENTAFLUORIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-29 WO disclosed
US-4304920-A ALKENYLOXYSILYLALKYL METHACRYLATE SHIN-ETSU CHEMICAL CO. LTD. (JP) 1981-12-08 US disclosed