Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398898 | 0.93 | TMEM97 (0.39) | TMEM97LSSPRCPOPRD1KCNH2 | |
| SCHEMBL11401507 | 0.91 | LSS (0.45) | TMEM97LSSPRCPOPRD1KCNH2 | |
| SCHEMBL11387453 | 0.85 | TMEM97 (0.38) | TMEM97LSSACHEOPRM1SIGMAR1 | |
| SCHEMBL11328342 | 0.81 | HTR2A (0.42) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11323073 | 0.81 | HTR2A (0.42) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11321439 | 0.80 | SIGMAR1 (0.44) | TMEM97OPRD1KCNH2OPRM1SIGMAR1 | |
| Oxalic Acid SCHEMBL11322198 | 0.78 | DRD2 (0.39) | TMEM97SIGMAR1 | |
| SCHEMBL11391165 | 0.75 | DRD2 (0.40) | TMEM97LSSKCNH2OPRM1SIGMAR1 | |
| SCHEMBL11369641 | 0.74 | DRD2 (0.43) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11326699 | 0.74 | DRD2 (0.39) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | disclosed |