Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.32 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544036 | 0.82 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL54760 | 0.82 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL961338 | 0.79 | DPP4 (0.38) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL31288119 | 0.78 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11608160 | 0.77 | NR1H3 (0.44) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL22401901 | 0.74 | DPP4 (0.44) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11603985 | 0.73 | DPP4 (0.41) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11424966 | 0.72 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11610021 | 0.71 | DPP4 (0.39) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL5940982 | 0.71 | MEN1 (0.43) | CASP3CYP1A2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209590-A | USING AN N-HALOALKYTHIOPHTHALIMIDE AS PROMOTER | CHEVRON RESEARCH COMPANY (US) | 1980-06-24 | — | — | US | claimed |
| US-4209590-A | USING AN N-HALOALKYTHIOPHTHALIMIDE AS PROMOTER | CHEVRON RESEARCH COMPANY (US) | 1980-06-24 | — | — | US | disclosed |