Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401902 | 0.85 | TDP1 (0.35) | DPP4NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL2156119 | 0.85 | CASP3 (0.46) | CASP3CYP1A2POLBMEN1KMT2A | |
| SCHEMBL30472938 | 0.85 | CASP3 (0.46) | CASP3CYP1A2POLBMEN1KMT2A | |
| SCHEMBL11610021 | 0.80 | DPP4 (0.39) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL54760 | 0.80 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL30544036 | 0.80 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL31288119 | 0.80 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11603985 | 0.79 | DPP4 (0.41) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL11608160 | 0.79 | NR1H3 (0.44) | DPP4NR1H2NR1H3CASP3CYP1A2 | |
| SCHEMBL961338 | 0.77 | DPP4 (0.38) | DPP4NR1H2NR1H3CASP3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213070-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | Epitas Biosciences (shanghai) Co., Ltd. (CN) | 2022-07-07 | — | — | US | disclosed |
| US-20200281202-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281202-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP51A1 | DPP4 952/4885NR1H2 2707/4885NR1H3 3098/4885 |
| US-20220213070-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | TDO2, TFPI, PPIG | DPP4 453/4885NR1H2 1929/4885NR1H3 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.