Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401901 | 0.79 | DPP4 (0.44) | DPP4NR1H2NR1H3ALDH1A1CASP3 | |
| SCHEMBL28061765 | 0.79 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3MEN1 | |
| SCHEMBL31288119 | 0.79 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3MEN1 | |
| SCHEMBL30544036 | 0.79 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3MEN1 | |
| SCHEMBL54760 | 0.79 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3MEN1 | |
| SCHEMBL11610021 | 0.79 | DPP4 (0.39) | DPP4NR1H2NR1H3DRD3ALDH1A1 | |
| SCHEMBL961338 | 0.76 | DPP4 (0.38) | DPP4NR1H2NR1H3CASP3MEN1 | |
| SCHEMBL11608160 | 0.74 | NR1H3 (0.44) | DPP4NR1H2NR1H3ALDH1A1CASP3 | |
| SCHEMBL11424975 | 0.73 | DPP4 (0.40) | DPP4NR1H2NR1H3CASP3RAB9A | |
| SCHEMBL13618811 | 0.73 | DRD3 (0.42) | DRD3ALDH1A1CASP3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |