Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401901 | 0.79 | DPP4 (0.44) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL11424975 | 0.77 | DPP4 (0.40) | NR1H3DPP4NR1H2CASP3LMNA | |
| SCHEMBL31288119 | 0.75 | DPP4 (0.40) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL54760 | 0.75 | DPP4 (0.40) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL28061765 | 0.75 | DPP4 (0.40) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL30544036 | 0.75 | DPP4 (0.40) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL11610021 | 0.75 | DPP4 (0.39) | NR1H3DPP4NR1H2CASP3TDP1 | |
| SCHEMBL11603985 | 0.74 | DPP4 (0.41) | NR1H3DPP4NR1H2CASP3LMNA | |
| SCHEMBL961338 | 0.73 | DPP4 (0.38) | NR1H3DPP4NR1H2CASP3KMT2A | |
| SCHEMBL11604335 | 0.71 | DPP4 (0.44) | NR1H3DPP4NR1H2CASP3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |