SCHEMBL114251

SCHEMBL114251

Cc1c(CC=O)oc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
KCNH2 Q12809 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
PGAM1 P18669 1/20 0.39
MAOA P21397 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
VKORC1 Q9BQB6 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SLC22A12 Q96S37 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31329246 1.00 KDM4E (0.42) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL4778349 0.79 ABCB1 (0.43) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL10238814 0.77 CYP2C19 (0.49) KDM4EKCNH2ALDH1A1MAPTHPGD
SCHEMBL13937435 0.77 CA12 (0.49) ALDH1A1MAPTHPGDCYP3A4HSD17B10
SCHEMBL12472939 0.76 MAPT (0.56) L3MBTL1SMN1; SMN2MAPTHPGDCYP3A4
SCHEMBL29184217 0.76 L3MBTL1 (0.40) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL4742417 0.76 KDM4E (0.42) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL1658639 0.76 KDM4E (0.42) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL13654189 0.76 KDM4E (0.42) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL3752508 0.76 PLK1 (0.43) KDM4EKCNH2L3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294906-A1 IMPROVEMENT IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-12-27 EP claimed
WO-2022175314-A1 IMPROVEMENT IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-08-25 WO claimed
US-10975327-B2 High performing, high impact bloom accord INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2021-04-13 US claimed
EP-3649184-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
WO-2019010265-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
WO-2019010263-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
EP-3197424-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
EP-3197422-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter & Gamble Company (US) 2017-08-02 EP claimed
EP-3197508-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
EP-3197511-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
WO-2016049396-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049455-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049407-A1 ABSORBENT ARTICLE COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049394-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049398-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-12630781-B2 Fragrance or flavour mixture SYMRISE AG (DE) 2026-05-19 US disclosed
US-12630783-B2 Muguet type fragrance compounds SYMRISE AG (DE) 2026-05-19 US disclosed
US-20060166857-A1 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes SYMRISE GMBH & CO. KG (DE) 2006-07-27 US disclosed
US-20060135400-A1 4-Cyclohexyl-2-butanol as an odiferous substance SYMRISE GMBH & CO. KG (DE) 2006-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630783-B2 Muguet type fragrance compounds MGAT1, RFT1, CPT1A KDM4E 590/4885KCNH2 476/4885L3MBTL1 337/4885
US-12630781-B2 Fragrance or flavour mixture NOTUM, FFAR2, FFAR1 KDM4E 2767/4885KCNH2 746/4885L3MBTL1 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.