Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.54 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433495 | 0.96 | PGR (0.59) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11431334 | 0.95 | PGR (0.57) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11423796 | 0.95 | PGR (0.66) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11433463 | 0.94 | PGR (0.67) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11433111 | 0.94 | PGR (0.58) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11431556 | 0.93 | PGR (0.59) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11438462 | 0.93 | ABCB11 (0.63) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11424014 | 0.92 | PGR (0.59) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11438787 | 0.92 | PGR (0.62) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11429769 | 0.92 | PGR (0.62) | PGRCYP3A4NR3C1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |