Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464812 | 0.79 | TDP1 (0.36) | TDP1KDM1AMEN1KMT2A | |
| SCHEMBL11250438 | 0.73 | LTA4H (0.36) | TDP1HTR2CSMN1; SMN2KDM1AALDH1A1 | |
| SCHEMBL5945055 | 0.69 | MTNR1A (0.38) | TDP1SMN1; SMN2GAAPARP10MEN1 | |
| SCHEMBL11320827 | 0.69 | MEN1 (0.38) | TDP1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL23270401 | 0.66 | TDP1 (0.35) | TDP1KDM1AMEN1KMT2A | |
| SCHEMBL1723277 | 0.66 | TDP1 (0.42) | TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3285217 | 0.65 | CYP1A2 (0.39) | TDP1HTR2CGAAALOX5 | |
| SCHEMBL5945052 | 0.64 | PARP10 (0.41) | PARP10MEN1KMT2A | |
| SCHEMBL5866514 | 0.63 | CHRNB2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| Carbamic Acid SCHEMBL28146970 | 0.62 | TDP1 (0.79) | TDP1SMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4237250-A | Polyurethanes containing aryl sulfonic acid alkyl ester groups | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |