Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CD40 | P25942 | 2/20 | 0.47 |
| ▸ | CD40LG | P29965 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431125 | 0.92 | MAPT (0.57) | MAPTRAB9ANPC1CASP6CTDSP1 | |
| SCHEMBL11439509 | 0.88 | RAB9A (0.55) | MAPTRAB9ANPC1CTDSP1ALDH1A1 | |
| SCHEMBL11436204 | 0.85 | CASP6 (0.65) | MAPTRAB9ACASP6CTDSP1APEX1 | |
| SCHEMBL11431241 | 0.84 | MAPT (0.55) | MAPTRAB9ANPC1CASP6CTDSP1 | |
| SCHEMBL11425994 | 0.84 | SMN1; SMN2 (0.56) | MAPTRAB9ANPC1CTDSP1ALDH1A1 | |
| SCHEMBL11423148 | 0.84 | POLB (0.51) | MAPTRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL11436268 | 0.83 | MAPT (0.57) | MAPTRAB9ANPC1CD40CD40LG | |
| SCHEMBL11425915 | 0.83 | CASP6 (0.63) | MAPTRAB9ANPC1CASP6CTDSP1 | |
| SCHEMBL11431595 | 0.82 | CASP6 (0.71) | MAPTRAB9ANPC1CASP6CTDSP1 | |
| SCHEMBL11430180 | 0.81 | RAB9A (0.54) | MAPTRAB9ANPC1CTDSP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |