Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CD40 | P25942 | 2/20 | 0.48 |
| ▸ | CD40LG | P29965 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431125 | 0.91 | MAPT (0.57) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL11431303 | 0.88 | RAB9A (0.54) | MAPTRAB9ANPC1APEX1ALDH1A1 | |
| SCHEMBL11431309 | 0.84 | SMN1; SMN2 (0.55) | MAPTRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL11422993 | 0.84 | POLB (0.50) | MAPTRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL11427680 | 0.84 | CASP6 (0.59) | MAPTRAB9AAPEX1ALDH1A1TRPV1 | |
| SCHEMBL11425189 | 0.83 | CD40 (0.53) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL11426443 | 0.83 | MAPT (0.55) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL11431241 | 0.83 | MAPT (0.55) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL10905209 | 0.83 | ENPP2 (0.51) | APEX1TRPV1ENPP2CA1CA2 | |
| SCHEMBL11350067 | 0.83 | TIMP3 (0.57) | APEX1ALDH1A1TRPV1ENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |