Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435442 | 0.91 | CASP6 (0.49) | CASP6CTDSP1ENPP2NPC1RAB9A | |
| SCHEMBL11427748 | 0.85 | CASP6 (0.47) | CASP6CTDSP1ENPP2NPC1RAB9A | |
| SCHEMBL11433010 | 0.85 | CASP6 (0.67) | CASP6CTDSP1ENPP2NPC1RAB9A | |
| SCHEMBL11441385 | 0.84 | ENPP2 (0.51) | CASP6CTDSP1ENPP2TNIKNPC1 | |
| SCHEMBL11435634 | 0.84 | ENPP2 (0.47) | CASP6CTDSP1ENPP2TNIKNPC1 | |
| SCHEMBL10907894 | 0.83 | ENPP2 (0.45) | CASP6CTDSP1ENPP2NPC1RAB9A | |
| SCHEMBL11342360 | 0.83 | HPSE (0.48) | CASP6CTDSP1ENPP2NPC1RAB9A | |
| SCHEMBL11208054 | 0.83 | CASP6 (0.62) | CASP6CTDSP1ENPP2TNIKNPC1 | |
| SCHEMBL11433700 | 0.83 | MAPT (0.55) | CTDSP1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL11426163 | 0.82 | CASP6 (0.73) | CASP6CTDSP1ENPP2TNIKNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |