Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427500 | 0.91 | ENPP2 (0.49) | ENPP2CASP6CTDSP1NPC1RAB9A | |
| SCHEMBL11442544 | 0.85 | CASP6 (0.63) | ENPP2CASP6CTDSP1NPC1RAB9A | |
| SCHEMBL11427835 | 0.84 | CASP6 (0.49) | ENPP2CASP6CTDSP1TNIKNPC1 | |
| SCHEMBL11208054 | 0.83 | CASP6 (0.62) | ENPP2CASP6CTDSP1TNIKNPC1 | |
| SCHEMBL11343138 | 0.83 | HPSE (0.46) | ENPP2CASP6CTDSP1NPC1RAB9A | |
| SCHEMBL10909166 | 0.83 | ENPP2 (0.43) | ENPP2CASP6CTDSP1NPC1RAB9A | |
| SCHEMBL11427748 | 0.83 | CASP6 (0.47) | ENPP2CASP6CTDSP1NPC1RAB9A | |
| SCHEMBL11426296 | 0.83 | MAPT (0.55) | CTDSP1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11441385 | 0.82 | ENPP2 (0.51) | ENPP2CASP6CTDSP1TNIKNPC1 | |
| SCHEMBL11427947 | 0.82 | CASP6 (0.48) | ENPP2CASP6CTDSP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |