Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NEU4 | Q8WWR8 | 2/20 | 0.33 |
| ▸ | NEU3 | Q9UQ49 | 2/20 | 0.33 |
| ▸ | NEU2 | Q9Y3R4 | 2/20 | 0.33 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543593 | 0.80 | SMN1; SMN2 (0.33) | SMN1; SMN2NPSR1 | |
| SCHEMBL13887303 | 0.79 | NFKB1 (0.32) | SMN1; SMN2NPSR1 | |
| SCHEMBL23095736 | 0.73 | — | — | |
| SCHEMBL11428317 | 0.71 | — | — | |
| SCHEMBL1355394 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL11426078 | 0.67 | OAT (0.36) | — | |
| SCHEMBL14653231 | 0.64 | SMN1; SMN2 (0.31) | SMN1; SMN2NPSR1 | |
| SCHEMBL9288572 | 0.61 | MAPK1 (0.35) | SMN1; SMN2 | |
| SCHEMBL10062135 | 0.61 | MAPK1 (0.33) | SMN1; SMN2 | |
| SCHEMBL12673693 | 0.61 | NFKB1 (0.33) | SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187316-A | ENZYME INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1980-02-05 | — | — | US | disclosed |