Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558268 | 0.87 | ACE (0.46) | CA9CA2DRD2DRD1KDM4E | |
| SCHEMBL11562455 | 0.83 | MMP9 (0.45) | HTT | |
| SCHEMBL11427641 | 0.81 | ACE (0.42) | FKBP1AALDH1A1TDP1 | |
| SCHEMBL11427389 | 0.80 | MAPT (0.41) | KDM4EPOLBMEN1KMT2AFKBP1A | |
| Hydrochloric Acid SCHEMBL11560085 | 0.80 | ACE (0.41) | FKBP1ATDP1 | |
| SCHEMBL11563644 | 0.72 | FKBP1A (0.42) | FKBP1AALDH1A1TDP1 | |
| SCHEMBL11562628 | 0.71 | ALDH1A1 (0.46) | DRD1KDM4EMAPK1ALDH1A1 | |
| SCHEMBL11433556 | 0.69 | MAPT (0.44) | POLBMEN1KMT2A | |
| SCHEMBL11554022 | 0.69 | BRD4 (0.38) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11557147 | 0.68 | ACE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4193997-A | ANTICOAGULANT, HTROMBOSIS, ANALGESICS, ANTIINFLAMMATORY | PARCOR (FR) | 1980-03-18 | — | — | US | disclosed |
| US-4147787-A | ANTICOAGULANTS | PARCOR (FR) | 1979-04-03 | — | — | US | disclosed |