Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441543 | 0.97 | HTT (0.47) | ADRA1DADRA1AADRA1BAOC3GAA | |
| SCHEMBL11426703 | 0.82 | KCNH2 (0.53) | SIGMAR1 | |
| SCHEMBL11435156 | 0.82 | HTT (0.45) | ADRA1DADRA1AADRA1BAOC3GAA | |
| SCHEMBL11436980 | 0.81 | DRD2 (0.51) | ADRA1DADRA1AADRA1BHTTSMPD1 | |
| SCHEMBL1966332 | 0.81 | AOC3 (0.59) | AOC3SMN1; SMN2SMPD1SIGMAR1 | |
| SCHEMBL11441540 | 0.80 | BCHE (0.54) | KMT2AMEN1 | |
| SCHEMBL11435175 | 0.80 | KCNH2 (0.50) | SIGMAR1 | |
| SCHEMBL11429882 | 0.80 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BAOC3GAA | |
| SCHEMBL28661867 | 0.78 | SMN1; SMN2 (0.65) | GAAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12909329 | 0.76 | HRH3 (0.64) | HTTSMN1; SMN2KMT2AMEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |