Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435156 | 0.91 | HTT (0.45) | DRD2DRD3HTTALDH1A1ADRA1D | |
| SCHEMBL11430223 | 0.84 | BCHE (0.51) | — | |
| SCHEMBL11441543 | 0.84 | HTT (0.47) | HTTALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL11429433 | 0.81 | ADRA1D (0.46) | HTTADRA1DADRA1AADRA1BSMPD1 | |
| SCHEMBL11442329 | 0.81 | MAPT (0.40) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29336126 | 0.79 | DRD2 (0.58) | DRD2DRD3DRD4 | |
| SCHEMBL11441561 | 0.77 | KDM4E (0.46) | DRD2DRD3HTTADRA1DADRA1A | |
| SCHEMBL11429461 | 0.76 | BCHE (0.52) | — | |
| SCHEMBL2352823 | 0.76 | CYP1A2 (0.48) | DRD2DRD3HTTCYP1A2CYP3A4 | |
| SCHEMBL6469311 | 0.73 | SMN1; SMN2 (0.57) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |