Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425748 | 0.91 | ADORA3 (0.41) | ADORA3PTGER4NPC1RAB9AMAPT | |
| SCHEMBL11432944 | 0.91 | ADORA3 (0.41) | ADORA3PTGER4NPC1RAB9AMAPT | |
| SCHEMBL10905526 | 0.86 | DHODH (0.44) | ADORA3PTGER4NPC1RAB9AMAPT | |
| SCHEMBL11424721 | 0.86 | DHODH (0.44) | ADORA3PTGER4NPC1RAB9AMAPT | |
| SCHEMBL11438820 | 0.85 | CASP6 (0.40) | ADORA3MAPTTP53MEN1KMT2A | |
| SCHEMBL11433104 | 0.85 | CASP6 (0.48) | ADORA3NPC1RAB9AMAPTMEN1 | |
| SCHEMBL11438812 | 0.83 | SENP2 (0.40) | ADORA3MAPTTP53MEN1KMT2A | |
| SCHEMBL11424104 | 0.83 | MEN1 (0.52) | NPC1RAB9AMAPTTP53MEN1 | |
| SCHEMBL11438930 | 0.83 | KDM4E (0.48) | ADORA3NPC1RAB9AMAPTMEN1 | |
| SCHEMBL11438895 | 0.82 | ADORA3 (0.41) | ADORA3PTGER4NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |