SCHEMBL11429698

SCHEMBL11429698

CCCCCCNS(=O)(=O)c1cc[c]cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
LMNA P02545 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
PKM P14618 3/20 0.56
KDM4E B2RXH2 1/20 0.56
HTT P42858 4/20 0.55
MAPK1 P28482 1/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
TSHR P16473 3/20 0.54
RECQL P46063 1/20 0.51
EPHX2 P34913 1/20 0.51
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11312451 1.00 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL9768680 1.00 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL5280742 1.00 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL9225790 0.98 ALDH1A1 (0.53) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL4708382 0.93 LMNA (0.55) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL7014515 0.86 CA12 (0.62) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL6291288 0.83 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL1279062 0.83 ALDH1A1 (0.82) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL5020960 0.83 ALDH1A1 (0.82) ALDH1A1LMNASMN1; SMN2PKMKDM4E
SCHEMBL579136 0.83 ALDH1A1 (0.82) ALDH1A1LMNASMN1; SMN2PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed